1188265-34-0

1188265-34-0 structure
1188265-34-0 structure
  • Name: Norfluoxetine-d5 hydrochloride
  • Chemical Name: 3-(2,3,4,5,6-pentadeuteriophenyl)-3-[4-(trifluoromethyl)phenoxy]propan-1-amine,hydrochloride
  • CAS Number: 1188265-34-0
  • Molecular Formula: C16H12D5ClF3NO
  • Molecular Weight: 336.79
  • Create Date: 2016-06-11 23:19:45
  • Modify Date: 2024-01-03 11:10:13
  • Norfluoxetine-d5 (hydrochloride) is deuterium labeled 3-Phenyl-3-(4-(trifluoromethyl)phenoxy)propan-1-amine hydrochloride.

Name 3-(2,3,4,5,6-pentadeuteriophenyl)-3-[4-(trifluoromethyl)phenoxy]propan-1-amine,hydrochloride
Synonyms Desmethylfluoxetine-d5 Hydrochloride
Description Norfluoxetine-d5 (hydrochloride) is deuterium labeled 3-Phenyl-3-(4-(trifluoromethyl)phenoxy)propan-1-amine hydrochloride.
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Molecular Formula C16H12D5ClF3NO
Molecular Weight 336.79
Exact Mass 336.12600
PSA 35.25000
LogP 5.67660