340316-62-3
340316-62-3 structure
- Name: SMIFH2
- Chemical Name: (5E)-1-(3-Bromophenyl)-5-(2-furylmethylene)-2-thioxodihydro-4,6(1 H,5H)-pyrimidinedione
- CAS Number: 340316-62-3
- Molecular Formula: C15H9BrN2O3S
- Molecular Weight: 377.21300
- Create Date: 2016-12-06 08:17:30
- Modify Date: 2025-08-23 11:13:12
-
SMIFH2 is a small molecule formin homology 2 domains inhibitor of formin-mediated actin assembly, targets formins from evolutionarily diverse organisms including yeast, nematode worm, and mice with IC50s of 5-15 uM.
| Name | (5E)-1-(3-Bromophenyl)-5-(2-furylmethylene)-2-thioxodihydro-4,6(1 H,5H)-pyrimidinedione |
|---|---|
| Synonyms | 1-(3-Bromophenyl)-5-(2-furanylmethylene)dihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione |
| Molecular Formula | C15H9BrN2O3S |
|---|---|
| Molecular Weight | 377.21300 |
| Exact Mass | 375.95200 |
| PSA | 98.13000 |
| LogP | 3.21430 |
| Storage condition | 2-8°C |
| Symbol |
GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301 |
| Precautionary Statements | P301 + P310 |
| RIDADR | UN 2811 6.1 / PGIII |