95385-38-9

95385-38-9 structure

Name: Tubulin polymerization-IN-57
Chemical Name: Tubulin polymerization-IN-57
CAS Number: 95385-38-9
Molecular Formula: C₁₉H₁₅N₃O₃
Molecular Weight: 333.34
Catalog: Signaling Pathways Cell Cycle/DNA Damage Microtubule/Tubulin
Create Date: 2024-04-02 14:55:03
Modify Date: 2024-04-02 14:55:03
Tubulin polymerization-IN-57 (compound 5a) is a tubulin inhibitor and is an α-naphthoxy-substituted carbendazim (HY-13582) derivative. Tubulin polymerization-IN-57 induces mitotic arrest and inhibits cancer cell proliferation[1].

Name	Tubulin polymerization-IN-57

Description	Tubulin polymerization-IN-57 (compound 5a) is a tubulin inhibitor and is an α-naphthoxy-substituted carbendazim (HY-13582) derivative. Tubulin polymerization-IN-57 induces mitotic arrest and inhibits cancer cell proliferation[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin
References	[1]. Cano-González L et al. Structure-Based Optimization of Carbendazim-Derived Tubulin Polymerization Inhibitors through Alchemical Free Energy Calculations. J Chem Inf Model. 2023 Nov 27;63(22):7228-7238.

Molecular Formula	C₁₉H₁₅N₃O₃
Molecular Weight	333.34