2415989-91-0
2415989-91-0 structure
- Name: SHP2-IN-23
- Chemical Name: SHP2-IN-23
- CAS Number: 2415989-91-0
- Molecular Formula: C24H23ClN8S
- Molecular Weight: 491.01
- Catalog: Signaling Pathways MAPK/ERK Pathway ERK
- Create Date: 2024-01-17 16:57:19
- Modify Date: 2024-01-17 16:57:19
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SHP2-IN-23 (compound 30) is an orally active SHP2 inhibitor (IC50=38 nM) with excellent in vivo efficacy and pharmacokinetic profiles. SHP2-IN-23 inhibits ERK phosphorylation with IC50=5 nM[1].
| Name | SHP2-IN-23 |
|---|
| Description | SHP2-IN-23 (compound 30) is an orally active SHP2 inhibitor (IC50=38 nM) with excellent in vivo efficacy and pharmacokinetic profiles. SHP2-IN-23 inhibits ERK phosphorylation with IC50=5 nM[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 38 nM (SHP2), 5 nM (pERK)[1] |
| References |
| Molecular Formula | C24H23ClN8S |
|---|---|
| Molecular Weight | 491.01 |