2769107-89-1

2769107-89-1 structure

2769107-89-1 structure

Name: MK-1468
Chemical Name: MK-1468
CAS Number: 2769107-89-1
Molecular Formula: C₂₆H₃₃ClN₄O₄
Molecular Weight: 501.02
Catalog: Signaling Pathways Autophagy LRRK2
Create Date: 2023-12-21 18:16:08
Modify Date: 2024-01-02 18:33:00
MK-1468 is a high selective and brain-penetrant inhibitor of LRRK2 with an IC50 of 0.8 nM. MK-1468 can be used in study Parkinson’s disease[1].

Name	MK-1468

Description	MK-1468 is a high selective and brain-penetrant inhibitor of LRRK2 with an IC50 of 0.8 nM. MK-1468 can be used in study Parkinson’s disease[1].
Related Catalog	Signaling Pathways >> Autophagy >> LRRK2 Research Areas >> Neurological Disease
References	[1]. Kattar SD, et al. Discovery of MK-1468: A Potent, Kinome-Selective, Brain-Penetrant Amidoisoquinoline LRRK2 Inhibitor for the Potential Treatment of Parkinson's Disease. J Med Chem. 2023 Oct 20.

Molecular Formula	C₂₆H₃₃ClN₄O₄
Molecular Weight	501.02