1224195-72-5

1224195-72-5 structure

Name: Cu(II)-Elesclomol
Chemical Name: Cu(II)-Elesclomol
CAS Number: 1224195-72-5
Molecular Formula: C₁₉H₁₈CuN₄O₂S₂
Molecular Weight: 462.05
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2024-03-15 21:57:41
Modify Date: 2025-09-18 18:51:16
Cu(II)-Elesclomol is a Cu2+ complex of Elesclomol (HY-12040). Cu(II)-Elesclomol induces apoptosis, causes a G1 cell cycle block and induces DNA double strand breaks in K562 cells. Cu(II)-Elesclomol also weakly inhibits DNA topoisomerase I. Cu(II)-Elesclomol has anticancer activity[1].

Name	Cu(II)-Elesclomol

Description	Cu(II)-Elesclomol is a Cu2+ complex of Elesclomol (HY-12040). Cu(II)-Elesclomol induces apoptosis, causes a G1 cell cycle block and induces DNA double strand breaks in K562 cells. Cu(II)-Elesclomol also weakly inhibits DNA topoisomerase I. Cu(II)-Elesclomol has anticancer activity[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase
References	[1]. Brian B Hasinoff, et al. Cellular mechanisms of the cytotoxicity of the anticancer drug elesclomol and its complex with Cu(II). hem Pharmacol. 2015 Feb 1;93(3):266-76. [2]. Brian B Hasinoff, et al. Cellular mechanisms of the cytotoxicity of the anticancer drug elesclomol and its complex with Cu(II). hem Pharmacol. 2015 Feb 1;93(3):266-76.

Molecular Formula	C₁₉H₁₈CuN₄O₂S₂
Molecular Weight	462.05