DC Chemicals Limited
China
Product Name: Romifidine
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Purity: 98.0%
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Romifidine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

65896-16-4

65896-16-4 structure

65896-16-4 structure

Name: Romifidine
Chemical Name: N-(2-Bromo-6-fluorophenyl)-4,5-dihydro-1H-imidazol-2-amine
CAS Number: 65896-16-4
Molecular Formula: C₉H₉BrFN₃
Molecular Weight: 258.090
Catalog: Signaling Pathways GPCR/G Protein Adrenergic Receptor
Create Date: 2018-03-03 08:00:00
Modify Date: 2024-01-03 14:08:50
Romifidine is an α2 adrenergic receptor agonist. Romifidine shows sedation effects in vivo[1][2].

Name	N-(2-Bromo-6-fluorophenyl)-4,5-dihydro-1H-imidazol-2-amine
Synonyms	Romifidina [Spanish] 2-(6-bromo-2-fluorophenylimino)-imidazolidine Romifidinum [Latin] 2-bromo-6-fluoro-N-(2-imidazolidinylidene)-benzamine 2-[(2-bromo-6-fluorophenyl)-imino]-imidazolidine N-(2-Bromo-6-fluorophenyl)-4,5-dihydro-1H-imidazol-2-amine 2-[(2-Brom-6-fluorphenyl)imino]imidazolidin Romifidina Romifidinum N-(2-bromo-6-fluoro-phenyl)-4,5-dihydro-1H-imidazol-2-amine (2-bromo-6-fluoro-phenyl)-(4,5-dihydro-1H-imidazol-2-yl)-amine 1H-Imidazol-2-amine, N-(2-bromo-6-fluorophenyl)-4,5-dihydro- Romifidine Sedivet

Description	Romifidine is an α2 adrenergic receptor agonist. Romifidine shows sedation effects in vivo[1][2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Neurological Disease
In Vivo	Romifidine (80 μg/kg; i.v. once) produces sedative effects with significantly greater drooping during the 45-90 min time period in welsh mountain ponies[1]. Romifidine (40, 80 and 120 mg/kg; i.v. at seven-day intervals) shows a shallower and shorter-lived sedation than with detomidine in horses[2].
References	[1]. England GC, et al. A comparison of the sedative effects of three alpha 2-adrenoceptor agonists (romifidine, detomidine and xylazine) in the horse. J Vet Pharmacol Ther. 1992 Jun;15(2):194-201. [2]. Hamm D, et al. Sedative and analgesic effects of detomidine and romifidine in horses. Vet Rec. 1995 Apr 1;136(13):324-7.

Density	1.7±0.1 g/cm3
Boiling Point	303.2±52.0 °C at 760 mmHg
Melting Point	110 °C
Molecular Formula	C₉H₉BrFN₃
Molecular Weight	258.090
Flash Point	137.2±30.7 °C
Exact Mass	256.996368
PSA	36.42000
LogP	1.02
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.662

HS Code	2933290090

HS Code	2933290090
Summary	2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%