2692692-00-3

2692692-00-3 structure

Name: (2R,3R)-Firazorexton
Chemical Name: (2R,3R)-Firazorexton
CAS Number: 2692692-00-3
Molecular Formula: C₂₂H₂₅F₃N₂O₄S
Molecular Weight: 470.51
Catalog: Signaling Pathways GPCR/G Protein Orexin Receptor (OX Receptor)
Create Date: 2024-09-19 01:07:07
Modify Date: 2024-09-19 01:07:07
(2R,3R)-Firazorexton ((2R,3R)-TAK-994 free base) is an isomer of Firazorexton (HY-137440). Firazorexton is an orally active, brain-penetrating orexin type 2 receptor (OX2R) agonist that may improve narcolepsy-like symptoms[1]..

Name	(2R,3R)-Firazorexton

Description	(2R,3R)-Firazorexton ((2R,3R)-TAK-994 free base) is an isomer of Firazorexton (HY-137440). Firazorexton is an orally active, brain-penetrating orexin type 2 receptor (OX2R) agonist that may improve narcolepsy-like symptoms[1]..
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Orexin Receptor (OX Receptor) Research Areas >> Neurological Disease
References	[1]. Ishikawa T, Hara H, Kawano A, Tohyama K, Kajita Y, Miyanohana Y, Koike T, Kimura H. TAK-994, a Novel Orally Available Brain-Penetrant Orexin 2 Receptor-Selective Agonist, Suppresses Fragmentation of Wakefulness and Cataplexy-Like Episodes in Mouse Models of Narcolepsy. J Pharmacol Exp Ther. 2023 Jun;385(3):193-204.

Molecular Formula	C₂₂H₂₅F₃N₂O₄S
Molecular Weight	470.51