4753-02-0

4753-02-0 structure

Name: Uridine,2'-bromo-2'-deoxy- (7CI,8CI,9CI)
Chemical Name: 2'-Bromo-2'-deoxy-D-uridine
CAS Number: 4753-02-0
Molecular Formula: C₉H₁₁BrN₂O₅
Molecular Weight: 307.10
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2016-10-27 07:49:12
Modify Date: 2024-01-24 18:06:09
2′-Bromo-2′-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2'-Bromo-2'-deoxy-D-uridine
Synonyms	21-Brom-21-desoxyuridin 2'-Bromo-2'-desoxyuridin Uridine, 2'-bromo-2'-deoxy- 2'-Bromo-2'-deoxyuridine 2'-bromo-2'-deoxy-uridine 2'-Brom-2'-desoxy-uridin 1-Piperidino-2-brom-1-phenyl-aethan 2'-Brom-2'-deoxy-uridin

Description	2′-Bromo-2′-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.