2170136-02-2

2170136-02-2 structure

Name: (Rac)-GSK-3484862
Chemical Name: (Rac)-GSK-3484862
CAS Number: 2170136-02-2
Molecular Formula: C₁₉H₁₉N₅OS
Molecular Weight: 365.45
Catalog: Research Areas Cancer
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(Rac)-GSK-3484862 is the inactive isomer of GSK-3484862 (HY-135146), and can be used as an experimental control. GSK-3484862 is a non-covalent inhibitor for DNA methyltransferase (Dnmt1). GSK-3484862 induces DNA hypomethylation to against cancer. GSK-3484862 mediates dramatic demethylation in murine embryonic stem cells with minimal non-specific toxicity[1][2].

Name	(Rac)-GSK-3484862

Description	(Rac)-GSK-3484862 is the inactive isomer of GSK-3484862 (HY-135146), and can be used as an experimental control. GSK-3484862 is a non-covalent inhibitor for DNA methyltransferase (Dnmt1). GSK-3484862 induces DNA hypomethylation to against cancer. GSK-3484862 mediates dramatic demethylation in murine embryonic stem cells with minimal non-specific toxicity[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Nathalia Azevedo Portilho, et al. The DNMT1 inhibitor GSK-3484862 mediates global demethylation in murine embryonic stem cells. [2]. Keystone Symposia 2019 - Epigenetics and Human Disease

Molecular Formula	C₁₉H₁₉N₅OS
Molecular Weight	365.45