2944459-58-7

2944459-58-7 structure

Name: HDAC-IN-60
Chemical Name: HDAC-IN-60
CAS Number: 2944459-58-7
Molecular Formula: C₂₀H₂₆N₂O₆
Molecular Weight: 390.43
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2024-09-23 16:32:33
Modify Date: 2024-09-23 16:32:33
HDAC-IN-60 (compound 21a) is a potent histone deacetylase (HDAC) inhibitor. HDAC-IN-60 can promote the intracellular generation of ROS, cause DNA damage, block the cell cycle at G2/M phase, and activate the mitochondria-related apoptotic pathway to induce cell apoptosis[1].

Name	HDAC-IN-60

Description	HDAC-IN-60 (compound 21a) is a potent histone deacetylase (HDAC) inhibitor. HDAC-IN-60 can promote the intracellular generation of ROS, cause DNA damage, block the cell cycle at G2/M phase, and activate the mitochondria-related apoptotic pathway to induce cell apoptosis[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> HDAC Signaling Pathways >> Epigenetics >> HDAC
References	[1]. Yang Y, et, al. Design, Synthesis, and Biological Evaluation of Histone Deacetylase Inhibitors Derived from Erianin and Its Derivatives. ChemMedChem. 2023 Jul 3;18(13):e202300108.

Molecular Formula	C₂₀H₂₆N₂O₆
Molecular Weight	390.43