Shanghai Nianxing Industrial Co., Ltd
China
Product Name: GPX4-IN-6
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Purity: 99.54%
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2922824-07-3

2922824-07-3 structure

2922824-07-3 structure

Name: GPX4-IN-6
Chemical Name: GPX4-IN-6
CAS Number: 2922824-07-3
Molecular Formula: C₁₈H₁₇BrFNO₅
Molecular Weight: 426.23
Catalog: Signaling Pathways Apoptosis Ferroptosis
Create Date: 2024-04-09 18:08:42
Modify Date: 2024-04-09 18:08:42
GPX4-IN-6 (Compound C25) is a GPX4 covalent inhibitor with an IC50 value of 0.13 μM. GPX4-IN-6 (Compound C25) can induce ferroptosis for the research of triple-negative breast cancer (TNBC) [1].

Name	GPX4-IN-6

Description	GPX4-IN-6 (Compound C25) is a GPX4 covalent inhibitor with an IC50 value of 0.13 μM. GPX4-IN-6 (Compound C25) can induce ferroptosis for the research of triple-negative breast cancer (TNBC) [1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Apoptosis >> Ferroptosis
Target	IC50: 0.13 μM (GPX4)[1]
References	[1]. Chen T, et al. Discovery of Novel Potent Covalent Glutathione Peroxidase 4 Inhibitors as Highly Selective Ferroptosis Inducers for the Treatment of Triple-Negative Breast Cancer. J Med Chem. 2023 Jul 27;66(14):10036-10059.

Molecular Formula	C₁₈H₁₇BrFNO₅
Molecular Weight	426.23