2924156-51-2

2924156-51-2 structure
2924156-51-2 structure
  • Name: Anti-inflammatory agent 55
  • Chemical Name: Anti-inflammatory agent 55
  • CAS Number: 2924156-51-2
  • Molecular Formula: C17H15N3O7
  • Molecular Weight: 373.32
  • Catalog: Signaling Pathways Immunology/Inflammation Interleukin Related
  • Create Date: 2024-07-17 11:16:36
  • Modify Date: 2024-07-17 11:16:36
  • Anti-inflammatory agent 55 (compound 9j) is a derivative of Coixol and has anti-inflammatory activity. Anti-inflammatory agent 54 inhibits the NF-κB pathway and downregulates the expression of iNOS, TNF-α, IL-6 and IL-1β. Anti-inflammatory agent 54 inhibits LPS-induced nitric oxide (NO) production in RAW264.7 macrophages (IC50: 0.8 μM) and exerts in vivo anti-inflammatory activity in a mouse auricular edema model[1].

Name Anti-inflammatory agent 55
Description Anti-inflammatory agent 55 (compound 9j) is a derivative of Coixol and has anti-inflammatory activity. Anti-inflammatory agent 54 inhibits the NF-κB pathway and downregulates the expression of iNOS, TNF-α, IL-6 and IL-1β. Anti-inflammatory agent 54 inhibits LPS-induced nitric oxide (NO) production in RAW264.7 macrophages (IC50: 0.8 μM) and exerts in vivo anti-inflammatory activity in a mouse auricular edema model[1].
Related Catalog
References

[1]. Cui E, et al. Discovery of Coixol Derivatives as Potent Anti-inflammatory Agents. J Nat Prod. 2023 Aug 25;86(8):1950-1959..  

Molecular Formula C17H15N3O7
Molecular Weight 373.32
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