777857-56-4
777857-56-4 structure
- Name: Scaff10-8
- Chemical Name: Scaff10-8
- CAS Number: 777857-56-4
- Molecular Formula: C22H18O6
- Molecular Weight: 378.37
- Catalog: Signaling Pathways Cell Cycle/DNA Damage ROCK
- Create Date: 2024-04-02 21:53:30
- Modify Date: 2024-04-02 21:53:30
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Scaff10-8 is an inhibitor of AKAP-Lbc-RhoA interaction that acts by promoting the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells.
| Name | Scaff10-8 |
|---|
| Description | Scaff10-8 is an inhibitor of AKAP-Lbc-RhoA interaction that acts by promoting the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells. |
|---|---|
| References | 1. Schrade K, Tröger J, Eldahshan A, Zühlke K, Abdul Azeez KR, Elkins JM, Neuenschwander M, Oder A, Elkewedi M, Jaksch S, Andrae K, Li J, Fernandes J, Müller PM, Grunwald S, Marino SF, Vukićević T, Eichhorst J, Wiesner B, Weber M, Kapiloff M, Rocks O, Daumke O, Wieland T, Knapp S, von Kries JP, Klussmann E. An AKAP-Lbc-RhoA interaction inhibitor promotes the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells. PLoS One. 2018 Jan 26;13(1):e0191423. doi: 10.1371/journal.pone.0191423. eCollection 2018. PubMed PMID: 29373579; PubMed Central PMCID: PMC5786306. |
| Molecular Formula | C22H18O6 |
|---|---|
| Molecular Weight | 378.37 |