20255-66-7

20255-66-7 structure

Name: N,N-Dimethyl(2H3)acetamide
Chemical Name: n,n-dimethylacetamide-2,2,2-d3
CAS Number: 20255-66-7
Molecular Formula: C₄H₆D₃NO
Molecular Weight: 90.139
Catalog: Research Areas Others
Create Date: 2018-06-26 12:12:07
Modify Date: 2024-01-11 21:16:48
N,N-Dimethylacetamide-d3 is the deuterium labeled N,N-Dimethylacetamide[1]. N,N-Dimethylacetamide (DMAc) is an inexpensive, common aprotic organic solvent[2].

Name	n,n-dimethylacetamide-2,2,2-d3
Synonyms	N,N-Dimethyl(H)acetamide 2,2,2-trideuterio-N,N-dimethyl-acetamide 2-<N,N-Dimethyl-acetamidinium>-thiosulfat d3-N,N-Dimethylacetamid N,N-Dimethyl-trideuteroacetamid Acetamide-d, N,N-dimethyl- N,N-Dimethyl-acetamidin-2-thiolsulfat N,N-Dimethylacetamid-D3

Description	N,N-Dimethylacetamide-d3 is the deuterium labeled N,N-Dimethylacetamide[1]. N,N-Dimethylacetamide (DMAc) is an inexpensive, common aprotic organic solvent[2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Sundaram S, et al. N,N-dimethylacetamide regulates the proinflammatory response associated with endotoxin and prevents preterm birth. Am J Pathol. 2013 Aug;183(2):422-30.