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2169925-98-6

2169925-98-6 structure

2169925-98-6 structure

Name: S-Gem
Chemical Name: S-Gem
CAS Number: 2169925-98-6
Molecular Formula: C₁₃H₁₅F₂N₃O₆S₂
Molecular Weight: 411.40
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2023-10-01 00:42:10
Modify Date: 2025-09-25 08:59:41
S-Gem is a TrxR-dependent prodrug of Gemcitabine (HY-17026) and selectively activated by TrxR. S-Gem shows less cytotoxicity compared to Gemcitabine[1].

Name	S-Gem

Description	S-Gem is a TrxR-dependent prodrug of Gemcitabine (HY-17026) and selectively activated by TrxR. S-Gem shows less cytotoxicity compared to Gemcitabine[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis Signaling Pathways >> Autophagy >> Autophagy
References	[1]. Li X, et, al. Combination of chemotherapy and oxidative stress to enhance cancer cell apoptosis. Chem Sci. 2020 Feb 25;11(12):3215-3222.

Molecular Formula	C₁₃H₁₅F₂N₃O₆S₂
Molecular Weight	411.40

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