Name | IRAK4-IN-28 |
---|
Description | IRAK4-IN-28 (compound 42) is an orally active IRAK4 inhibitor (IC50=8.9 nM). IRAK4-IN-28 has binding affinity for IRAK4 with a Kd of 0.58 nM. IRAK4-IN-28 can be used in the research of inflammation and autoimmune diseases[1]. |
---|---|
Related Catalog | |
Target |
IC50:8.9 nM (IRAK4)[1], IC50:>30 nM (hERG)[1], Kd:0.58 nM (IRAK4)[1], Kd:140 nM (IRAK1)[1] |
References |
Molecular Formula | C27H31N9O3 |
---|---|
Molecular Weight | 529.59 |