2745197-24-2

2745197-24-2 structure

Name: HIV-1 inhibitor-57
Chemical Name: HIV-1 inhibitor-57
CAS Number: 2745197-24-2
Molecular Formula: C₂₅H₂₄FN₅O₃S
Molecular Weight: 493.55
Catalog: Signaling Pathways Anti-infection HIV
Create Date: 2023-10-20 19:37:47
Modify Date: 2024-02-18 11:29:45
HIV-1 inhibitor-57 (Compound 12g) is a HIV inhibitor. HIV-1 inhibitor-57 is active against wild-type and five prevalent NNRTI-resistant HIV-1 strains with EC50 values ranging from 0.024 to 0.0010 μM. HIV-1 inhibitor-57 forms additional interactions with residues around the binding site in HIV-1 RT[1].

Name	HIV-1 inhibitor-57

Description	HIV-1 inhibitor-57 (Compound 12g) is a HIV inhibitor. HIV-1 inhibitor-57 is active against wild-type and five prevalent NNRTI-resistant HIV-1 strains with EC50 values ranging from 0.024 to 0.0010 μM. HIV-1 inhibitor-57 forms additional interactions with residues around the binding site in HIV-1 RT[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection
References	[1]. Jiang X, et al. Discovery of novel diarypyrimidine derivatives bearing six-membered non-aromatic heterocycles as potent HIV-1 NNRTIs with improved anti-resistance and drug-like profiles. Eur J Med Chem. 2023 Oct 5;258:115605.

Molecular Formula	C₂₅H₂₄FN₅O₃S
Molecular Weight	493.55