2279945-77-4

2279945-77-4 structure
2279945-77-4 structure
  • Name: Glucocerebrosidase-IN-1 hydrochloride
  • Chemical Name: Glucocerebrosidase-IN-1 hydrochloride
  • CAS Number: 2279945-77-4
  • Molecular Formula: C13H28ClNO3
  • Molecular Weight: 281.82
  • Catalog: Research Areas Neurological Disease
  • Create Date: 2023-10-03 09:23:15
  • Modify Date: 2026-06-18 14:30:03
  • Glucocerebrosidase-IN-1 (compound 11a) hydrochloride is a potent and selective GCase (glucocerebrosidase) inhibitor, with an IC50 of 29.3 μM and a Ki of 18.5 μM. Glucocerebrosidase-IN-1 hydrochloride can be used for the research of Gaucher disease (GD) and Parkinson’s disease (PD)[1].

Name Glucocerebrosidase-IN-1 hydrochloride
Description Glucocerebrosidase-IN-1 (compound 11a) hydrochloride is a potent and selective GCase (glucocerebrosidase) inhibitor, with an IC50 of 29.3 μM and a Ki of 18.5 μM. Glucocerebrosidase-IN-1 hydrochloride can be used for the research of Gaucher disease (GD) and Parkinson’s disease (PD)[1].
Related Catalog
References

[1]. Clemente F, et al. Glucocerebrosidase (GCase) activity modulation by 2-alkyl trihydroxypiperidines: Inhibition and pharmacological chaperoning. Bioorg Chem. 2020 May;98:103740.  

Molecular Formula C13H28ClNO3
Molecular Weight 281.82
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