2136278-38-9

2136278-38-9 structure

Name: DCZ3301
Chemical Name: DCZ3301
CAS Number: 2136278-38-9
Molecular Formula: C₂₀H₁₆ClF₃N₆O₂
Molecular Weight: 464.83
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2023-10-19 19:00:46
Modify Date: 2024-01-23 19:15:44
DCZ3301 is a potent aryl-guanidino inhibitor. DCZ3301 inhibits cell proliferation, induces G2/M cell cycle arrest and apoptosis. DCZ3301 inhibits the activation of the PI3K/AKT pathway by downregulating the protein expression of PI3K and phosphorylation of AKT. DCZ3301 can be used in research of cancer[1].

Name	DCZ3301

Description	DCZ3301 is a potent aryl-guanidino inhibitor. DCZ3301 inhibits cell proliferation, induces G2/M cell cycle arrest and apoptosis. DCZ3301 inhibits the activation of the PI3K/AKT pathway by downregulating the protein expression of PI3K and phosphorylation of AKT. DCZ3301 can be used in research of cancer[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> PI3K/Akt/mTOR >> PI3K Signaling Pathways >> PI3K/Akt/mTOR >> Akt
References	[1]. Xiao W, et, al. DCZ3301, a novel aryl-guanidino inhibitor, induces cell apoptosis and cell cycle arrest via suppressing the PI3K/AKT pathway in T-cell leukemia/lymphoma. Acta Biochim Biophys Sin (Shanghai). 2018 Jul 1;50(7):643-650.

Molecular Formula	C₂₀H₁₆ClF₃N₆O₂
Molecular Weight	464.83