2916371-59-8

2916371-59-8 structure
2916371-59-8 structure
  • Name: Cisd2 agonist 2
  • Chemical Name: Cisd2 agonist 2
  • CAS Number: 2916371-59-8
  • Molecular Formula: C14H14N2O4S
  • Molecular Weight: 306.34
  • Catalog: Research Areas Inflammation/Immunology
  • Create Date: 2023-10-19 12:50:56
  • Modify Date: 2025-08-25 08:23:29
  • Cisd2 agonist 2 (compound 6) is an orally active Cisd2 activator (EC50=191 nM), while the Cisd2 levels is correlated with nonalcoholic fatty liver disease (NAFLD). Cisd2 agonist 2 has no significant toxicity in vivo in Cisd2hKO-het mice (heterozygous hepatocyte-specific Cisd2 knockout)[1].

Name Cisd2 agonist 2
Description Cisd2 agonist 2 (compound 6) is an orally active Cisd2 activator (EC50=191 nM), while the Cisd2 levels is correlated with nonalcoholic fatty liver disease (NAFLD). Cisd2 agonist 2 has no significant toxicity in vivo in Cisd2hKO-het mice (heterozygous hepatocyte-specific Cisd2 knockout)[1].
Related Catalog
Target

CDGSH iron sulfur domain-containing 2 (Cisd2)[1]

References

[1]. Yao CH, et al. Discovery of tetrasubstituted thiophenes as Cisd2 activators: A potential novel therapeutic option in nonalcoholic fatty liver disease. Eur J Med Chem. 2023 Oct 5;258:115583.  

Molecular Formula C14H14N2O4S
Molecular Weight 306.34
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