1936431-44-5

1936431-44-5 structure
1936431-44-5 structure
  • Name: CBP-IN-1
  • Chemical Name: CBP-IN-1
  • CAS Number: 1936431-44-5
  • Molecular Formula: C27H33F2N7O
  • Molecular Weight: 509.59
  • Catalog: Signaling Pathways Epigenetics Epigenetic Reader Domain
  • Create Date: 2023-10-22 19:15:29
  • Modify Date: 2024-04-09 18:35:49
  • CBP-IN-1 (compound 12) is a potent CBP inhibitor, with an IC50 of 1.5 nM. CBP-IN-1 also inhibits CBP BRET and BRD4(1), with IC50 values of 690 and 3100 nM, respectively[1].

Name CBP-IN-1
Description CBP-IN-1 (compound 12) is a potent CBP inhibitor, with an IC50 of 1.5 nM. CBP-IN-1 also inhibits CBP BRET and BRD4(1), with IC50 values of 690 and 3100 nM, respectively[1].
Related Catalog
References

[1]. Romero FA, et al. GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP). J Med Chem. 2017 Nov 22;60(22):9162-9183.  

Molecular Formula C27H33F2N7O
Molecular Weight 509.59