211190-38-4
211190-38-4 structure
- Name: Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2
- Chemical Name: Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2
- CAS Number: 211190-38-4
- Molecular Formula: C42H63FN12O8
- Molecular Weight: 883.02
- Catalog: Signaling Pathways GPCR/G Protein Protease-Activated Receptor (PAR)
- Create Date: 2023-09-30 12:12:15
- Modify Date: 2024-04-05 17:48:29
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Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 is a biological active peptide. (Protease activated receptor 1 (PAR-1) belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. This peptide is a PAR-1 selective agonist displaying a high level of specificity to PAR-1 over PAR-2. The specificity of peptide was evaluated in cell-based calcium signaling assay using HEK293 cells. PAR-1 selective agonists can be used to study PAR-1 activation in vivo. In addition to its varied cellular effects of thrombin, PAR-1 has also been shown to coordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as 'coagulation type'.)
| Name | Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 |
|---|
| Description | Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 is a biological active peptide. (Protease activated receptor 1 (PAR-1) belongs to a subfamily of G-protein coupled receptors and is known to mediate the cellular effects of thrombin. This peptide is a PAR-1 selective agonist displaying a high level of specificity to PAR-1 over PAR-2. The specificity of peptide was evaluated in cell-based calcium signaling assay using HEK293 cells. PAR-1 selective agonists can be used to study PAR-1 activation in vivo. In addition to its varied cellular effects of thrombin, PAR-1 has also been shown to coordinate with PAR-4 and regulate thrombin-induced hepatocellular carcinoma harboring thrombin formation within the tumor environment classified as 'coagulation type'.) |
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| Related Catalog |
| Molecular Formula | C42H63FN12O8 |
|---|---|
| Molecular Weight | 883.02 |