211108-48-4

211108-48-4 structure

Name: tert-Butyl 4-[(Trimethylsilanyl)oxy]-3,6-dihydro-2H-pyridine-1-carboxylate
Chemical Name: tert-butyl 4-trimethylsilyloxy-3,6-dihydro-2H-pyridine-1-carboxylate
CAS Number: 211108-48-4
Molecular Formula: C₁₃H₂₅NO₃Si
Molecular Weight: 271.428
Catalog: Pharmaceutical intermediate Heterocyclic compound Pyridine compound Dihydropyridine
Create Date: 2018-12-24 10:17:36
Modify Date: 2025-08-25 16:17:59

Name	tert-butyl 4-trimethylsilyloxy-3,6-dihydro-2H-pyridine-1-carboxylate
Synonyms	1(2H)-Pyridinecarboxylic acid, 3,6-dihydro-4-[(trimethylsilyl)oxy]-, 1,1-dimethylethyl ester tert-butyl-4-[(trimethylsilyl)oxy]-3,6-dihydropyridine-1(2H)-carboxylate tert-butyl 4-trimethylsilanyloxy-3,6-dihydro-2H-pyridine-1-carboxylate 1-tert-butoxycarbonyl-1,2,3,6-tetrahydro-4-(trimethylsilyloxy)pyridine N-t-butyloxycarbonyl-4-trimethylsilyloxy-1,2,3,6-tetrahydropyridine tert-Butyl 4-((trimethylsilyl)oxy)-5,6-dihydropyridine-1(2H)-carboxylate 4-trimethylsilanyloxy-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester 2-Methyl-2-propanyl 4-[(trimethylsilyl)oxy]-3,6-dihydro-1(2H)-pyridinecarboxylate

Density	1.0±0.1 g/cm3
Boiling Point	300.5±42.0 °C at 760 mmHg
Molecular Formula	C₁₃H₂₅NO₃Si
Molecular Weight	271.428
Flash Point	135.5±27.9 °C
Exact Mass	271.160370
PSA	38.77000
LogP	3.39
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.476

HS Code	2933399090

75-77-4

79099-07-3

~93%

211108-48-4

Literature: ARRAY BIOPHARMA INC. Patent: WO2008/124323 A1, 2008 ; Location in patent: Page/Page column 39-40 ; WO 2008/124323 A1

79099-07-3

~69%

211108-48-4

Literature: ASTRAZENECA AB Patent: WO2004/5295 A1, 2004 ; Location in patent: Page 61-62 ;

27607-77-8

79099-07-3

~80%

211108-48-4

Literature: NOVIRA THERAPEUTICS, INC.; HARTMAN, George D.; FLORES, Osvaldo A. Patent: WO2013/96744 A1, 2013 ; Location in patent: Page/Page column 222; 223 ;

Precursor 3
75-77-4 79099-07-3 27607-77-8
DownStream 8
373604-28-5 211108-50-8 1070896-59-1 188869-05-8
1208864-35-0 1174020-40-6 1174020-42-8 934536-10-4

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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