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2896204-90-1

2896204-90-1 structure

2896204-90-1 structure

Name: Anti-inflammatory agent 41
Chemical Name: Anti-inflammatory agent 41
CAS Number: 2896204-90-1
Molecular Formula: C₃₃H₂₅N₃O₅
Molecular Weight: 543.57
Create Date: 2023-11-26 10:28:41
Modify Date: 2024-04-06 11:33:57
Anti-inflammatory agent 41 (13a) significantly inhibit lipopolysaccharide (LPS)-induced expression of the proinflammatory cytokines IL-6 and TNF-α on J774A.1, THP-1 and LX-2 cells, and inhibits the activation of the NF-κB pathway[1].

Name	Anti-inflammatory agent 41

Description	Anti-inflammatory agent 41 (13a) significantly inhibit lipopolysaccharide (LPS)-induced expression of the proinflammatory cytokines IL-6 and TNF-α on J774A.1, THP-1 and LX-2 cells, and inhibits the activation of the NF-κB pathway[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Interleukin Related Research Areas >> Inflammation/Immunology
In Vitro	Anti-inflammatory agent 41 (13a) 显著减少了LPS诱导的p65在J774A.1巨噬细胞中的核转位。
References	[1]. Jun Yang, et al. Discovery of 4-oxo-N-phenyl-1,4-dihydroquinoline-3-carboxamide derivatives as novel anti-inflammatory agents for the treatment of acute lung injury and sepsis. Eur J Med Chem. 2023 Mar 5;249:115144.

Molecular Formula	C₃₃H₂₅N₃O₅
Molecular Weight	543.57

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