- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: N-Boc-piperazine
- Price: Check
- Purity: 98.0%
- Stocking Period: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: N-Boc-piperazine
- Price: ￥90.0/25g ￥248.0/100g ￥918.0/500g
- Purity: 95.0%
- Stocking Period: Inquiry
- Contact: Liu jia
- Email: 2130147988@qq.com
- DC Chemicals Limited
- China
- Product Name: N-Boc-piperazine
- Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 1-N-Boc-Piperazine
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: CAS:57260-71-6 tert-Butyl 1-piperazinecarboxylate
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
- Email: info@tianfuchem.com
57260-71-6
57260-71-6 structure
- Name: N-Boc-piperazine
- Chemical Name: 1-Boc-piperazine
- CAS Number: 57260-71-6
- Molecular Formula: C9H18N2O2
- Molecular Weight: 186.251
- Catalog: Pharmaceutical intermediate Heterocyclic compound Piperazine
- Create Date: 2018-07-12 23:22:13
- Modify Date: 2025-08-21 18:08:27
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N-Boc-piperazine is a Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTAC PD-1/PD-L1 degrader-1 (HY-131183)[1].
| Name | 1-Boc-piperazine |
|---|---|
| Synonyms |
piperazine-1-carboxylic acid tert-butyl ester
1-Piperazinecarboxylic acid, 1,1-dimethylethyl ester BOC-PIPERAZINE 2-Methyl-2-propanyl 1-piperazinecarboxylate 1-Boc piperzine t-Butyl 1-piperazincarboxylate tert-butyl piperazine-1-carboxylate 1,1-Dimethylethyl 1-piperazinecarboxylate 1-BOC-Piperazine PIBOC MFCD00075265 tert-butyl tetrahydropyrazine-1(2H)-carboxylate N-BOC-PIPERAZINE tert-butyl l-piperazinecarboxylate 1-N-BOC-PIPERAZINE RARECHEM AR PA 0026 BOC-PAZ N-Boc-piperazine; tert-butyl piperazine-1-carboxylate tert-Butyl 1-piperazinecarboxylate N-Boc-piperazine N Boc-Piperazine |
| Description | N-Boc-piperazine is a Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTAC PD-1/PD-L1 degrader-1 (HY-131183)[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 258.0±15.0 °C at 760 mmHg |
| Melting Point | 47-49ºC |
| Molecular Formula | C9H18N2O2 |
| Molecular Weight | 186.251 |
| Flash Point | 109.8±20.4 °C |
| Exact Mass | 186.136826 |
| PSA | 41.57000 |
| LogP | 0.55 |
| Vapour Pressure | 0.0±0.5 mmHg at 25°C |
| Index of Refraction | 1.467 |
| Storage condition | Refrigerator |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2933990090 |
| Precursor 9 | |
|---|---|
| DownStream 10 | |
![4-(4-Boc-1-piperazinyl)-5-bromo-7H-pyrrolo[2,3-d]pyrimidine structure](https://image.chemsrc.com/caspic/185/1072027-36-1.png)
| HS Code | 2933599090 |
|---|---|
| Summary | 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |