Name | WU-FA-01 |
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Description | WU-FA-01, a hydrogenated derivative of WU-FA-00, is an antibacterial agent that exhibits high levels of antibacterial activity against Gram-positive strains and also has some anti-inflammatory activity[1]. |
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Related Catalog | |
In Vitro | WU-FA-01(0-25 µg/mL, 24 h) 对革兰氏阳性菌具有剂量依赖性的抑制剂作用,而对革兰氏阴性菌株没有抑制作用[1]。 |
In Vivo | WU-FA-01(2000-8000µg/mL) 对 TPA 诱导的小鼠耳模型水肿具有剂量依赖性的抑制作用,可以有效保护 TPA 诱导的皮肤炎症[1]。 Animal Model: TPA-induced skin inflammation in female Kunming mice[1] Dosage: 2000, 4000 and 8000 µg/mL Administration: 20 µL of acetone-loaded agent topically applied to the right ear Result: Significantly reduced TPA-induced ear edema by 48.16%, 113.97% and 137.32%, respectively, at concentrations of 2000, 4000 and 8000 µg/mL. |
References |
Molecular Formula | C34H52O9 |
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Molecular Weight | 604.77 |