324022-01-7
324022-01-7 structure
- Name: ERRγ agonist-2
- Chemical Name: ERRγ agonist-2
- CAS Number: 324022-01-7
- Molecular Formula: C27H21N5O2
- Molecular Weight: 447.49
- Catalog: Research Areas Infection
- Create Date: 2023-06-09 17:58:16
- Modify Date: 2024-04-06 13:52:26
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ERRγ agonist-2 is a potent and selective ERRγ inverse agonist with a Kd value of 6.5 μM. ERRγ agonist-2 inhibits the expression of hepcidin, fibrinogen and gluconeogenic genes. ERRγ agonist-2 has antimicrobial, anti-coagulant and antidiabetic activities[1].
| Name | ERRγ agonist-2 |
|---|
| Description | ERRγ agonist-2 is a potent and selective ERRγ inverse agonist with a Kd value of 6.5 μM. ERRγ agonist-2 inhibits the expression of hepcidin, fibrinogen and gluconeogenic genes. ERRγ agonist-2 has antimicrobial, anti-coagulant and antidiabetic activities[1]. |
|---|---|
| Related Catalog | |
| Target |
ERRγ:6.5 μM (Kd) |
| In Vitro | ERRγ agonist-2 (1-10 μM; 293T 细胞) 抑制 ERRγ 的 PGC-1α 依赖性转录活性，对 ERRα 和 ERRβ 的抑制作用微弱[1]。 ERRγ agonist-2 (10 μM; AML12 细胞) 抑制铁调素、纤维蛋白原和糖异生基因的表达[1]。 |
| References |
| Molecular Formula | C27H21N5O2 |
|---|---|
| Molecular Weight | 447.49 |