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1795122-12-1

1795122-12-1 structure

1795122-12-1 structure

Name: Urapidil-d4
Chemical Name: Urapidil-d4
CAS Number: 1795122-12-1
Molecular Formula: C₂₀H₂₅D₄N₅O₃
Molecular Weight: 391.50
Catalog: Signaling Pathways GPCR/G Protein 5-HT Receptor
Create Date: 2023-04-20 19:25:34
Modify Date: 2025-08-24 22:30:27
Urapidil-d4 is the deuterium labeled Urapidil[1]. Urapidil is an α1 adrenoreceptor antagonist and a 5-HT1A receptor agonist[2].

Name	Urapidil-d4

Description	Urapidil-d4 is the deuterium labeled Urapidil[1]. Urapidil is an α1 adrenoreceptor antagonist and a 5-HT1A receptor agonist[2].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
Target	5-HT1A Receptor
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Bopp C, et al. The effect of urapidil, an alpha-1 adrenoceptor antagonist and a 5-HT1A agonist, on the vascular tone of the porcine coronary and pulmonary arteries, the rat aorta and the human pulmonary artery. Eur J Pharmacol. 2016 May 15;779:53-8.

Molecular Formula	C₂₀H₂₅D₄N₅O₃
Molecular Weight	391.50

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