2839311-21-4

2839311-21-4 structure

Name: mHTT-IN-1
Chemical Name: mHTT-IN-1
CAS Number: 2839311-21-4
Molecular Formula: C₁₈H₁₉N₇OS
Molecular Weight: 381.45
Catalog: Research Areas Neurological Disease
Create Date: 2023-06-20 17:54:57
Modify Date: 2025-08-27 08:23:15
mHTT-IN-1 (Example 1) is a potent mutant huntingtin (mHTT) inhibitor. mHTT is toxic and a major cause of the inherited autosomal dominant neurodegenerative disorder, Huntington's disease (HD). mHTT-IN-1 conducts the reduction of mHTT with an EC50 value of 46 nM[1].

Name	mHTT-IN-1

Description	mHTT-IN-1 (Example 1) is a potent mutant huntingtin (mHTT) inhibitor. mHTT is toxic and a major cause of the inherited autosomal dominant neurodegenerative disorder, Huntington's disease (HD). mHTT-IN-1 conducts the reduction of mHTT with an EC50 value of 46 nM[1].
Related Catalog	Research Areas >> Neurological Disease
References	[1]. Brom, et al. Preparation of thiazolopyrimidinone derivatives and uses thereof. World Intellectual Property Organization, WO2022194801 A1. 2022-09-22.

Molecular Formula	C₁₈H₁₉N₇OS
Molecular Weight	381.45