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78249-43-1

78249-43-1 structure
78249-43-1 structure

Name 1,2-(Methylenedioxy)-1,2-demethylcolchicine
Synonyms cornigerine
Density 1.35g/cm3
Boiling Point 743.5ºC at 760 mmHg
Molecular Formula C21H21NO6
Molecular Weight 383.39500
Flash Point 403.5ºC
Exact Mass 383.13700
PSA 83.09000
LogP 2.97400
Index of Refraction 1.623

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AC8587100
CHEMICAL NAME :
Acetamide, N-(6,7,8,10-tetrahydro-4,11-dimethoxy-10-oxoheptaleno (1,2-e)-1,3- benzodioxol-8-yl)-, (S)-
CAS REGISTRY NUMBER :
78249-43-1
LAST UPDATED :
198912
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C21-H21-N-O6
MOLECULAR WEIGHT :
383.43

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
64 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 26,1365,1983

~73%

78249-43-1 structure

78249-43-1

Literature: Kitajima, Mariko; Tanaka, Akiko; Kogure, Noriyuki; Takayama, Hiromitsu Tetrahedron Letters, 2008 , vol. 49, # 2 p. 257 - 260

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78249-43-1 structure

78249-43-1

Literature: Roesner, Manfred; Hsu, Fu-Lian; Brossi, Arnold Journal of Organic Chemistry, 1981 , vol. 46, # 18 p. 3686 - 3688

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78249-43-1 structure

78249-43-1

Literature: Roesner, Manfred; Hsu, Fu-Lian; Brossi, Arnold Journal of Organic Chemistry, 1981 , vol. 46, # 18 p. 3686 - 3688

~%

78249-43-1 structure

78249-43-1

Literature: Roesner, Manfred; Hsu, Fu-Lian; Brossi, Arnold Journal of Organic Chemistry, 1981 , vol. 46, # 18 p. 3686 - 3688