912789-08-3
912789-08-3 structure
- Name: ISX-3
- Chemical Name: ISX-3
- CAS Number: 912789-08-3
- Molecular Formula: C16H15ClN4O2
- Molecular Weight: 330.77
- Catalog: Research Areas Metabolic Disease
- Create Date: 2023-05-24 16:44:15
- Modify Date: 2025-08-26 17:22:58
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ISX-3 is a potent anti-adipogenic and pro-osteogenic agent. ISX-3 increases the expression of PPARγ. ISX-3 has the potential for the research of osteopenia and osteoporosis[1].
| Name | ISX-3 |
|---|
| Description | ISX-3 is a potent anti-adipogenic and pro-osteogenic agent. ISX-3 increases the expression of PPARγ. ISX-3 has the potential for the research of osteopenia and osteoporosis[1]. |
|---|---|
| Related Catalog | |
| In Vitro | ISX-3 (0-100,000 nM; 10 days) 显示出对脂滴积累的刺激作用和对 ALP 诱导的抑制作用[1]。 ISX-3 (50 µM; 2 days) 在存在 MDI 的情况下增加 hBMSCs 中 PPARγ 的表达[1]。 Western Blot Analysis[1] Cell Line: hBMSCs Concentration: 50 µM Incubation Time: 2 days Result: Increased the PPARγ expression level in the presence of MDI (0.5 mM isobutyl methylxanthine, 1 μM dexamethasone and 1 μM insulin). |
| References |
| Molecular Formula | C16H15ClN4O2 |
|---|---|
| Molecular Weight | 330.77 |