78617-94-4

78617-94-4 structure

Name: Blue FPG-A trisodium
Chemical Name: Blue FPG-A trisodium
CAS Number: 78617-94-4
Molecular Formula: C₂₉H₁₇ClN₇Na₃O₁₁S₃
Molecular Weight: 840.10
Catalog: Signaling Pathways GPCR/G Protein P2Y Receptor
Create Date: 2023-04-09 15:41:25
Modify Date: 2023-04-09 15:41:25
Blue FPG-A trisodium is a selective antagonist of P2X1 receptor and P2Y1 receptor with IC50 values of 35.5 μM and 2.6 μM, respectively. Blue FPG-A trisodium is a structural isomer of the components of Reactive Blue 2 (RB2)[1].

Name	Blue FPG-A trisodium

Description	Blue FPG-A trisodium is a selective antagonist of P2X1 receptor and P2Y1 receptor with IC50 values of 35.5 μM and 2.6 μM, respectively. Blue FPG-A trisodium is a structural isomer of the components of Reactive Blue 2 (RB2)[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> P2Y Receptor Research Areas >> Inflammation/Immunology Signaling Pathways >> Membrane Transporter/Ion Channel >> P2X Receptor
Target	p2x1 Receptor:35.5 μM (IC50) P2Y1 Receptor:2.6 μM (IC50)
In Vitro	Blue FPG-A trisodium (RB 2 para) (1、3.2、10、32 和 100 μM) 抑制 α、β-亚甲基 ATP (α、β-MeATP) 诱导的大鼠输精管 (RVD) 收缩和 5’-o-(2-硫代二磷酸腺苷) (ADPβS) 诱导的卡巴胆碱 (Carbachol，HY-B1208) 预处理的豚鼠大肠带绦虫 (GPTC) 的松弛[1]。
References	[1]. Glänzel M, et al. Constitutional isomers of Reactive Blue 2 - selective P2Y-receptor antagonists? Eur J Med Chem. 2003 Mar;38(3):303-12.

Molecular Formula	C₂₉H₁₇ClN₇Na₃O₁₁S₃
Molecular Weight	840.10