259200-30-1

259200-30-1 structure

Name: (2R,3S)-Brassinazole
Chemical Name: (2R,3S)-Brassinazole
CAS Number: 259200-30-1
Molecular Formula: C₁₈H₁₈ClN₃O
Molecular Weight: 327.81
Catalog: Research Areas Metabolic Disease
Create Date: 2023-05-05 23:03:51
Modify Date: 2025-08-28 21:00:14
Brassinazole (0.5, 1, 5 μM) causes markedly deformed seedlings, whose morphology is similar to that of BR-deficient mutants. Brassinazole causes cress dwarfism, altering leaf morphology such as the typical downward curl and dark green appearance of Arabidopsis BR-deficient mutants. However, administration of 10 nM BR reversed dwarfism[1].

Name	(2R,3S)-Brassinazole

Description	Brassinazole (0.5, 1, 5 μM) causes markedly deformed seedlings, whose morphology is similar to that of BR-deficient mutants. Brassinazole causes cress dwarfism, altering leaf morphology such as the typical downward curl and dark green appearance of Arabidopsis BR-deficient mutants. However, administration of 10 nM BR reversed dwarfism[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
Target	Brassinosteroid (BR) biosynthesis[1]
In Vitro	Brassinazole (0.5, 1, 5 μM) 显着导致幼苗畸形，其形态与 BR 缺陷突变体相似。Brassinazole 会导致水芹侏儒症，改变叶片形态，例如拟南芥 BR 缺陷突变体会有的典型的向下卷曲和深绿色外观。然而，施用 10 nM BR可逆转侏儒症[1]。
References	[1]. Yoshida Shigeo, et al. Preparation of (1,2,4-triazolyl)alkanols as specific inhibitors of brassinosteroid biosynthesis: Japan, JP2000053657. 2000-02-22. [2]. Asami T, et al. Mode of action of brassinazole: a specific inhibitor of brassinosteroid biosynthesis[M]. 2000. [3]. T Asami, et al. Characterization of Brassinazole, a Triazole-Type Brassinosteroid Biosynthesis Inhibitor. Plant Physiol. 2000 May;123(1):93-100.

Molecular Formula	C₁₈H₁₈ClN₃O
Molecular Weight	327.81