2396411-71-3

2396411-71-3 structure

Name: Lepunafusp alfa
Chemical Name: Research Grade Lepunafusp alfa (DHC02002)
CAS Number: 2396411-71-3
Molecular Formula:
Molecular Weight:
Catalog: Research Areas Neurological Disease
Create Date: 2023-04-06 15:52:04
Modify Date: 2024-04-08 19:57:18
Lepunafusp alfa (JR-171) is a BBB-penetrable fusion protein consisting of J-Brain Cargo and IDUA (a lysosomal enzyme, α-L-iduronidase). Lepunafusp alfa can reduce concentration of heparan sulfate (HS) and dermatan sulfate (DS). Lepunafusp alfa can be used for research of mucopolysaccharidosis type I[1][2].

Name	Research Grade Lepunafusp alfa (DHC02002)

Description	Lepunafusp alfa (JR-171) is a BBB-penetrable fusion protein consisting of J-Brain Cargo and IDUA (a lysosomal enzyme, α-L-iduronidase). Lepunafusp alfa can reduce concentration of heparan sulfate (HS) and dermatan sulfate (DS). Lepunafusp alfa can be used for research of mucopolysaccharidosis type I[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. Jeong GU, et al. Non-clinical evaluation of a blood-brain barrier-penetrating enzyme for the treatment of mucopolysaccharidosis type I. Molecular Genetics and Metabolism. 2019. 126 (2), S83-S84.

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