2241724-48-9
2241724-48-9 structure
- Name: Omodenbamab
- Chemical Name: Omodenbamab
- CAS Number: 2241724-48-9
- Molecular Formula:
- Molecular Weight:
- Catalog: Signaling Pathways Anti-infection Bacterial
- Create Date: 2023-02-24 09:56:47
- Modify Date: 2024-09-11 10:34:38
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Omodenbamab is an anti-SpA (Staphylococcal protein A) humanized monoclonal antibody with a KD value of 0.0467 nM. Omodenbamab circumvents a key S. aureus evasion mechanism by targeting the cell wall moiety Protein A (SpA). Omodenbamab can be used in research of S. aureus bloodstream infection[1].
| Name | Omodenbamab |
|---|
| Description | Omodenbamab is an anti-SpA (Staphylococcal protein A) humanized monoclonal antibody with a KD value of 0.0467 nM. Omodenbamab circumvents a key S. aureus evasion mechanism by targeting the cell wall moiety Protein A (SpA). Omodenbamab can be used in research of S. aureus bloodstream infection[1]. |
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| Related Catalog | |
| In Vitro | Omodenbamab (514-G3)与 S. aureus 结合并使 Fc 区暴露以供 FcγR1A 受体结合[1]。Omodenbamab (10 μg/mL; 30 min, 1.5 hr, and 2.5 hr) 支持人类血细胞对 S. aureus 的调理吞噬作用[1]。 |
| In Vivo | Omodenbamab (514-G3; 2.5 mg/mice and 10 mg/mice; i.v.) 在菌血症模型中保护小鼠免受 MRSA 的致死攻击[1]。 Animal Model: Balb/C mice with MRSA in a bacteremia model[1] Dosage: 2.5 mg/mice and 10 mg/mice Administration: Intravenous injection Result: Increased mouse Balb/C mice with MRSA in a bacteremia model survival. |
| References |
| No Any Chemical & Physical Properties |