2247828-39-1
2247828-39-1 structure
- Name: NPTC
- Chemical Name: NPTC
- CAS Number: 2247828-39-1
- Molecular Formula: C16H22N2O5
- Molecular Weight: 322.36
- Create Date: 2023-01-17 19:10:13
- Modify Date: 2024-09-17 18:34:47
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Description NPTC is a reagent developed in the Wipf lab to install a Tempoc protecting group. The Tempoc group is useful for protecting primary, secondary, and heterocyclic amines and is complimentary to both Boc and Cbz protecting groups. Tempoc deprotection can be performed under mild reductive conditions with in situ generated Cu(I) species or by thermolysis at 135 °C. Description NPTC is a reagent developed in the Wipf lab to install a Tempoc protecting group. The Tempoc group is useful for protecting primary, secondary, and heterocyclic amines and is complimentary to both Boc and Cbz protecting groups. Tempoc deprotection can be performed under mild reductive conditions with in situ generated Cu(I) species or by thermolysis at 135 °C.
| Name | NPTC |
|---|---|
| Synonyms | 4-Nitrophenyl (2,2,6,6-tetramethylpiperidin-1-yl) carbonate |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 399.8±44.0 °C at 760 mmHg |
| Molecular Formula | C16H22N2O5 |
| Molecular Weight | 322.36 |
| Flash Point | 195.6±28.4 °C |
| Exact Mass | 322.152863 |
| LogP | 4.90 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.555 |