Chemical Name: Urea crosslinker – C₂₋arm, NHS ester
CAS Number: 211029-82-2
Molecular Formula: C13H14N4O9
Molecular Weight: 370.27
Create Date: 2023-01-17 18:54:20
Modify Date: 2025-08-23 18:39:23
Description The ureido-2,2´-diacetic acid bis(hydroxysuccinimide) ester, is the shortest version of MS-cleavable urea-based lysine-lysine reactive homobifunctional cross-linkers, featuring a C2-arm. At neutral or slightly basic pH, it irreversibly crosslinks the neighbouring lysine groups. The presence of the symmetrical urea moiety which is prone to collision-induced dissociation, allows for the unambiguous distinguishing of crosslinks in tandem CID-MS experiments.
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