100891-36-9

100891-36-9 structure

Name: PKI (5-24),amide
Chemical Name: PKI (5-24),amide
CAS Number: 100891-36-9
Molecular Formula: C₉₄H₁₄₉N₃₃O₃₀
Molecular Weight: 2221.40
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK PKA
Create Date: 2023-01-14 19:32:53
Modify Date: 2025-08-25 19:08:13
PKI (5-24),amide (IP20-amide) is a 20-residue peptide that corresponds to the active portion of the heat-stable inhibitor protein of cAMP-dependent protein kinase. PKI (5-24),amide is a potent cAMP-dependent protein kinase (PKA) (PKA) inhibitor with a Ki of 2.3 nM[1].

Name	PKI (5-24),amide

Description	PKI (5-24),amide (IP20-amide) is a 20-residue peptide that corresponds to the active portion of the heat-stable inhibitor protein of cAMP-dependent protein kinase. PKI (5-24),amide is a potent cAMP-dependent protein kinase (PKA) (PKA) inhibitor with a Ki of 2.3 nM[1].
Related Catalog	Signaling Pathways >> Protein Tyrosine Kinase/RTK >> PKA Signaling Pathways >> Stem Cell/Wnt >> PKA Research Areas >> Neurological Disease
References	[1]. D B Glass, et al. Primary structural determinants essential for potent inhibition of cAMP-dependent protein kinase by inhibitory peptides corresponding to the active portion of the heat-stable inhibitor protein. J Biol Chem. 1989 May 25;264(15):8802-10.

Molecular Formula	C₉₄H₁₄₉N₃₃O₃₀
Molecular Weight	2221.40