| Name | Pepinemab |
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| Description | Pepinemab (VX 15/2503) is a human monoclonal antibody against SEMA4D, a signalling protein 4D (SEMA4D), also known as CD100, which is a regulator of neuronal development and plays a role in a variety of cellular processes. Pepinemab can be used in the study of various neurodegenerative diseases such as Alzheimer's disease by blocking the activity of SEMA4D[1]. |
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| Related Catalog | |
| In Vitro | Pepinemab(VX 15/2503)(48 h) 显著抑制原代人类星形细胞 CC-2565 中葡萄糖转运蛋白 (GLUT-1) 和单羧酸转运蛋白 (MCT)4 的表达,并抑制 SEMA4D 引起的星形细胞葡萄糖摄取的减少[1]。 |
| References |
| No Any Chemical & Physical Properties |