1931944-80-7

1931944-80-7 structure
1931944-80-7 structure
  • Name: Donanemab
  • Chemical Name: Donanemab
  • CAS Number: 1931944-80-7
  • Molecular Formula:
  • Molecular Weight:
  • Catalog: Research Areas Neurological Disease
  • Create Date: 2023-01-22 11:26:07
  • Modify Date: 2024-01-03 08:45:51
  • Donanemab (LY3002813) is a humanized IgG1 monoclonal antibody directed at an N‐terminal pyroglutamate amyloid beta (Aβ) epitope. Donanemab has the potential for early Alzheimer's disease research[1][2].

Name Donanemab
Description Donanemab (LY3002813) is a humanized IgG1 monoclonal antibody directed at an N‐terminal pyroglutamate amyloid beta (Aβ) epitope. Donanemab has the potential for early Alzheimer's disease research[1][2].
Related Catalog
In Vitro Donanemab 是一种针对 N 末端焦谷氨酸 Aβ 表位的人源化 IgG1 抗体,该表位仅存在于已建立的斑块中。Donanemab 对该表位具有特异性,并且未显示与其他 Aβ 种类、神经递质或其受体的脱靶结合[2]。
References

[1]. Stephen Loucian Lowe, et al. Donanemab (LY3002813) dose-escalation study in Alzheimer's disease. Alzheimers Dement (N Y). 2021 Feb 14;7(1):e12112.  

[2]. Mark A Mintun, et al. Donanemab in Early Alzheimer's Disease. N Engl J Med. 2021 May 6;384(18):1691-1704.  

No Any Chemical & Physical Properties
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