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176785-25-4

176785-25-4 structure

176785-25-4 structure

Name: [Arg-15,20,21,Leu17]-PACAP-Gly-Lys-Arg-NH2
Chemical Name: [Arg-15,20,21,Leu17]-PACAP-Gly-Lys-Arg-NH2
CAS Number: 176785-25-4
Molecular Formula: C₁₅₇H₂₅₃N₅₃O₄₂
Molecular Weight: 3555.02
Catalog: Research Areas Metabolic Disease
Create Date: 2023-01-24 20:32:58
Modify Date: 2024-01-10 11:26:24
[Arg-15,-20,-21,Leu17]-PACAP-Gly-Lys-Arg-NH2 (BM-PACAP) is a synthetic PACAP 1-27 (HY-P0176) analogue with relaxant effect[1].

Name	[Arg-15,20,21,Leu17]-PACAP-Gly-Lys-Arg-NH2

Description	[Arg-15,-20,-21,Leu17]-PACAP-Gly-Lys-Arg-NH2 (BM-PACAP) is a synthetic PACAP 1-27 (HY-P0176) analogue with relaxant effect[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease Research Areas >> Neurological Disease
In Vitro	[Arg-15,-20,-21,Leu17]-PACAP-Gly-Lys-Arg-NH2 (BM-PACAP) (0.1 μM; 0-5 h) 比 PACAP 1-27 在体外对人支气管的平滑肌舒张作用更久[1]。 [Arg-15,-20,-21,Leu17]-PACAP-Gly-Lys-Arg-NH2 (0.3-3 μM; 0-6 h) 引起浓度依赖性松弛，在豚鼠气管中具有非常相似的最大松弛剂效果和效力[2]。
References	[1]. Yoshihara S, et al. Long-lasting smooth-muscle relaxation by a novel PACAP analogue in human bronchi. Regul Pept. 2004 Dec 15;123(1-3):161-5. [2]. Yoshihara S, et al. Long lasting smooth muscle relaxation by a novel PACAP analogue in guinea-pig and primate airways in vitro. Br J Pharmacol. 1997 Aug;121(8):1730-4.

Molecular Formula	C₁₅₇H₂₅₃N₅₃O₄₂
Molecular Weight	3555.02