2797026-97-0
2797026-97-0 structure
- Name: Acazicolcept
- Chemical Name: Acazicolcept
- CAS Number: 2797026-97-0
- Molecular Formula:
- Molecular Weight:
- Catalog: Research Areas Inflammation/Immunology
- Create Date: 2023-01-26 22:15:05
- Modify Date: 2024-04-12 22:01:12
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Acazicolcept (ALPN-101), an Fc fusion protein, is a dual inducible T cell costimulator (ICOS)/CD28 antagonist. Acazicolcept has anti-inflammatory activities[1].
| Name | Acazicolcept |
|---|
| Description | Acazicolcept (ALPN-101), an Fc fusion protein, is a dual inducible T cell costimulator (ICOS)/CD28 antagonist. Acazicolcept has anti-inflammatory activities[1]. |
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| Related Catalog | |
| In Vivo | Azacicolcept (267-400 μg/mouse; i.p.; twice a week; for 6 weeks) 可减少皮肤和肺纤维化并缓解肺动脉高压[1]。 Animal Model: Six-week-old female BALB/c mice induced by hypochlorous acid (HOCL)[1] Dosage: 267 μg/mouse and 400 μg/mouse Administration: i.p.; twice a week; for 6 weeks Result: Induced a significant decrease in dermal thickness, collagen content, myofibroblast number, and inflammatory infiltrates characterized by B cells, T cells, neutrophils, and macrophages. |
| References |
| No Any Chemical & Physical Properties |