1005192-31-3
1005192-31-3 structure
- Name: Tubulin polymerization-IN-38
- Chemical Name: Tubulin polymerization-IN-38
- CAS Number: 1005192-31-3
- Molecular Formula: C31H50N4O8S
- Molecular Weight: 638.82
- Catalog: Signaling Pathways Cell Cycle/DNA Damage Microtubule/Tubulin
- Create Date: 2023-01-16 10:58:33
- Modify Date: 2025-09-20 17:59:23
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Tubulin polymerization-IN-38 a Tubulysin (HY-128914) analogue, is a potent anticancer agent. Tubulin polymerization-IN-38 inhibits tubulin polymerisation and thereby inducing apoptosis. Tubulin polymerization-IN-38 has cytotoxicity against cancer cells[1].
| Name | Tubulin polymerization-IN-38 |
|---|
| Description | Tubulin polymerization-IN-38 a Tubulysin (HY-128914) analogue, is a potent anticancer agent. Tubulin polymerization-IN-38 inhibits tubulin polymerisation and thereby inducing apoptosis. Tubulin polymerization-IN-38 has cytotoxicity against cancer cells[1]. |
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| Related Catalog | |
| Target |
Tubulin polymerisation[1] |
| In Vitro | Tubulin polymerization-IN-38 (example 5) exhibits cytotoxicity against L929, SW-480 and KB-3-1 with IC50s of 2.2 ng/mL, 0.35 ng/mL and 1.5 ng/mL, respectively[1]. |
| References |
[1]. Jonathan A. Ellman, et al. Tubulysin d analogues. WO2009012958A2. |
| Molecular Formula | C31H50N4O8S |
|---|---|
| Molecular Weight | 638.82 |