2797225-47-7
2797225-47-7 structure
- Name: PfGSK3/PfPK6-IN-2
- Chemical Name: PfGSK3/PfPK6-IN-2
- CAS Number: 2797225-47-7
- Molecular Formula: C24H25Cl2N5OS
- Molecular Weight: 502.46
- Catalog: Signaling Pathways PI3K/Akt/mTOR GSK-3
- Create Date: 2022-11-21 19:56:22
- Modify Date: 2024-04-04 17:29:27
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PfGSK3/PfPK6-IN-2 is a potent dual PfGSK3/PfPK6 (Plasmodium falciparum GSK3/PK6) inhibitor (IC50: 172 nM and 11 nM respectively). PfGSK3/PfPK6-IN-2 can be used in the research of Malaria[1].
| Name | PfGSK3/PfPK6-IN-2 |
|---|
| Description | PfGSK3/PfPK6-IN-2 is a potent dual PfGSK3/PfPK6 (Plasmodium falciparum GSK3/PK6) inhibitor (IC50: 172 nM and 11 nM respectively). PfGSK3/PfPK6-IN-2 can be used in the research of Malaria[1]. |
|---|---|
| Related Catalog | |
| Target |
Plasmodium falciparum GSK3/PK6 (PfGSK3/PfPK6)[1] |
| In Vitro | PfGSK3/PfPK6-IN-2 (compound 23d) inhibits P. falciparum 3D7 load in erythrocytes (EC50: 552 nM)[1]. PfGSK3/PfPK6-IN-2 (2 μM) shows cytotoxicity against HepG2 cells[1]. |
| Molecular Formula | C24H25Cl2N5OS |
|---|---|
| Molecular Weight | 502.46 |