32204-93-6
32204-93-6 structure
- Name: Glucagon (22-29)
- Chemical Name: Glucagon (22-29)
- CAS Number: 32204-93-6
- Molecular Formula: C49H71N11O12S
- Molecular Weight: 1038.22
- Catalog: Research Areas Metabolic Disease
- Create Date: 2022-12-11 18:10:34
- Modify Date: 2024-01-16 09:45:15
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Glucagon (22-29) is partial agonist of Glucagon (19–29). Glucagon specifically inhibits the Ca2+ pump in liver plasma membranes independently of adenylate cyclase activation[1][2].
| Name | Glucagon (22-29) |
|---|
| Description | Glucagon (22-29) is partial agonist of Glucagon (19–29). Glucagon specifically inhibits the Ca2+ pump in liver plasma membranes independently of adenylate cyclase activation[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | Glucagon (22-29) produces only a 5-15% maximal inhibition of (Ca2+-Mg2+) ATPase, with a low potency (Ki=1 μM), similar to that of native glucagon[1]. Glucagon (22-29) (10 nM) evokes an early small decrease of cell contraction when added alone and an 18% significant positive inotropic effect when added in combination with 30 nM glucagon. Glucagon (22-29) thus appears to act as a partial agonist of miniglucagon[2]. Glucagon (22-29) consists of the COOH-terminal part of miniglucagon but lacks the three Ala1g-Gln20-Asp21 residues[2]. |
| Molecular Formula | C49H71N11O12S |
|---|---|
| Molecular Weight | 1038.22 |