546100-66-7

546100-66-7 structure

Name: lucPpy-IN-1
Chemical Name: WAY-350568
CAS Number: 546100-66-7
Molecular Formula: C₂₅H₂₃N₅O
Molecular Weight: 409.48
Catalog: Research Areas Others
Create Date: 2022-11-30 11:17:50
Modify Date: 2024-04-06 10:56:04
lucPpy-IN-1 (compound 9) is an ATP-dependent luciferase from Photinus pyralis (lucPpy) inhibitor with an IC50 value of 4.0 µM. lucPpy-IN-1 can be used for the research of target’s druggability[1].

Name	WAY-350568
Synonyms	Methanone, [2-(4-methylphenyl)-4-quinolinyl][4-(2-pyrimidinyl)-1-piperazinyl]-

Description	lucPpy-IN-1 (compound 9) is an ATP-dependent luciferase from Photinus pyralis (lucPpy) inhibitor with an IC50 value of 4.0 µM. lucPpy-IN-1 can be used for the research of target’s druggability[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
Target	IC50: 4.0 µM (lucPpy)[1]
In Vitro	lucPpy-IN-1 (0.1 nM-100 µM) inhibits activity of lucPpy with an IC50 value of 4.0 µM[1].
References	[1]. Auld DS, et al. A basis for reduced chemical library inhibition of firefly luciferase obtained from directed evolution. J Med Chem. 2009 Mar 12;52(5):1450-8.