442898-75-1

442898-75-1 structure

442898-75-1 structure

Name: HSP90-IN-22
Chemical Name: WAY-326817
CAS Number: 442898-75-1
Molecular Formula: C₂₅H₃₀N₄O₃
Molecular Weight: 434.53
Create Date: 2022-12-05 18:36:09
Modify Date: 2023-10-20 18:33:49
HSP90-IN-22 (Compound 35) is an Hsp90 inhibitor with antiproliferative properties on cells with IC50 values of 3.65 μM for MCF7 breast cancer cells and 2.71 μM for SKBr3 breast cancer cells, respectively.

Name	WAY-326817
Synonyms	Benzamide, N-[2-(4-ethyl-1-piperazinyl)-4-methyl-6-quinolinyl]-3,4-dimethoxy-

Description	HSP90-IN-22 (Compound 35) is an Hsp90 inhibitor with antiproliferative properties on cells with IC50 values of 3.65 μM for MCF7 breast cancer cells and 2.71 μM for SKBr3 breast cancer cells, respectively.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> HSP Signaling Pathways >> Cell Cycle/DNA Damage >> HSP
References	[1]. Jiang F, et al. Identification and optimization of novel 6-acylamino-2-aminoquinolines as potent Hsp90 C-terminal inhibitors. Eur J Med Chem. 2017 Dec 1;141:1-14.

Molecular Formula	C₂₅H₃₀N₄O₃
Molecular Weight	434.53