207920-87-4
207920-87-4 structure
- Name: L-I-OddU
- Chemical Name: L-I-OddU
- CAS Number: 207920-87-4
- Molecular Formula: C8H9IN2O5
- Molecular Weight: 340.07
- Catalog: Signaling Pathways Cell Cycle/DNA Damage DNA/RNA Synthesis
- Create Date: 2022-11-15 00:52:07
- Modify Date: 2025-08-21 09:30:46
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L-I-OddU, a L-5'-halo- dioxolane nucleoside analogue, is a potent and selective anti-Epstein-Barr virus (EBV) agent with an EC50 value of 0.03μM. L-I-OddU has low cytotoxicity with a CC50 value of 1000 nM. L-I-OddU has antiviral activity by suppressing replicative EBV DNA and viral protein synthesis[1][2].
| Name | L-I-OddU |
|---|
| Description | L-I-OddU, a L-5'-halo- dioxolane nucleoside analogue, is a potent and selective anti-Epstein-Barr virus (EBV) agent with an EC50 value of 0.03μM. L-I-OddU has low cytotoxicity with a CC50 value of 1000 nM. L-I-OddU has antiviral activity by suppressing replicative EBV DNA and viral protein synthesis[1][2]. |
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| Related Catalog | |
| In Vitro | L-I-OddU (1 μM; H1 cells) inhibits Epstein-Barr virus (EBV) replication and decreases the linear form of EBV DNA[1]. L-I-OddU (0.25-2 μM; 24 h; H1 and L5 cells) has a major metabolite is L-I-OddUMP and increases the amount of the mono- and diphosphate metabolites formed in H1 cells in a dose-dependent manner[1]. |
| Molecular Formula | C8H9IN2O5 |
|---|---|
| Molecular Weight | 340.07 |