221662-50-6
221662-50-6 structure
- Name: L-2'-Fd4C
- Chemical Name: L-2'-Fd4C
- CAS Number: 221662-50-6
- Molecular Formula: C9H10FN3O3
- Molecular Weight: 227.19
- Catalog: Signaling Pathways Anti-infection HBV
- Create Date: 2022-11-22 10:54:41
- Modify Date: 2024-01-07 11:01:36
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L-2'-Fd4C, is an l-nucleoside analogue. L-2'-Fd4C has anti-human immunodeficiency virus (HIV) and anti-hepatitis B virus (HBV) activity[1].
| Name | L-2'-Fd4C |
|---|
| Description | L-2'-Fd4C, is an l-nucleoside analogue. L-2'-Fd4C has anti-human immunodeficiency virus (HIV) and anti-hepatitis B virus (HBV) activity[1]. |
|---|---|
| Related Catalog | |
| In Vitro | L-2'-Fd4C (0-10 μM; 9 d; HepG2-2.2.15 cells) inhibits anti-hepatitis B virus (HBV) replication with an EC50 value of 0.002 μM[1]. |
| In Vivo | L-2'-Fd4C (100 mg/kg; i.p.; daily, for 7 d) has antihepadnavirus potency in HBV-transgenic mice[1]. Animal Model: HBV-transgenic mice[1] Dosage: 100 mg/kg Administration: Intraperitoneal injection; daily, for 7 days Result: Had a reduction of HBV levels in their blood comparable to that produced by Lamivudine (HY-B0250). |
| Molecular Formula | C9H10FN3O3 |
|---|---|
| Molecular Weight | 227.19 |